Association Analysis of Two Polymorphisms in Neuregulin 1 Gene in a Turkish Schizophrenia Sample

Objective: NRG1 is one of the genes that was reported to have susceptibility alleles effecting phenotype schizophrenia. There are many SNPs (single nucleotide polymorphisms) located in gene with suspected which were associated In this study, we investigated potential associations between schizophrenia and polymorphisms rs4560751 rs3802160. Material Methods: We collected DNA samples 96 patients diagnosed for 100 healthy controls living Malatya-Turkey. genotyped two mentioned above compared case control groups distributions genotypes. also tested dominant models. used Chi-Squared test hypothesis testing. Results: No significant differences seen genotypes screened. Conclusion: The results our experiments statistical tests done indicated population screened there no sufficient evidence support association rs3802160